Article
Molecular sequence data of hepatitis B virus and genetic diversity after vaccination.
American journal of epidemiology - 15 Dec 2009
van Ballegooijen W Marijn, van Houdt Robin, Bruisten Sylvia M, Boot Hein J, Coutinho Roel A, Wallinga Jacco
Abstract excerpt
The effect of vaccination programs on transmission of infectious disease is usually assessed by monitoring programs that rely on notifications of symptomatic illness. For monitoring of infectious diseases with a high proportion of asymptomatic cases or a low reporting rate, molecular sequence data combined with modern coalescent-based techniques offer a complementary tool to assess transmission. Here, the authors...
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