Article
Biomolecular network reconstruction identifies T-cell homing factors associated with survival in colorectal cancer.
Gastroenterology - 1 Apr 2010
Mlecnik Bernhard, Tosolini Marie, Charoentong Pornpimol, Kirilovsky Amos, Bindea Gabriela, Berger Anne, Camus Matthieu, Gillard Mélanie, Bruneval Patrick, Fridman Wolf-Herman, Pagès Franck, Trajanoski Zlatko, Galon Jérôme
Abstract excerpt
BACKGROUND & AIMS: Colorectal cancer is a complex disease involving immune defense mechanisms within the tumor. Herein, we used data integration and biomolecular network reconstruction to generate hypotheses about the mechanisms underlying immune responses in colorectal cancer that are relevant t...
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