Optimality properties of a proposed precursor to the genetic code.

doi:10.1103/PhysRevE.80.032901

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Article

Optimality properties of a proposed precursor to the genetic code.

Physical review. E, Statistical, nonlinear, and soft matter physics - 1 Sept 2009

Butler Thomas, Goldenfeld Nigel

Abstract excerpt

We calculate the optimality score of a doublet precursor to the canonical genetic code with respect to mitigating the effects of point mutations and compare our results to corresponding ones for the canonical genetic code. We find that the proposed precursor is much less optimal than that of the canonical code. Our results render unlikely the notion that the doublet precursor was an intermediate state in the...

Topics

Evolution, Molecular
Genetic Code
Models, Genetic
Mutation

Source

Open in PubMed

Identifiers

PMID: 19905163
DOI: 10.1103/PhysRevE.80.032901

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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