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Article

The conserved active site tryptophan of thioredoxin has no effect on its redox properties.

Protein science : a publication of the Protein Society - 1 Jan 2010

Roos Goedele, Geerlings Paul, Messens Joris

Abstract excerpt

In Staphylococcus aureus thioredoxin (Trx) it has been shown that mutation of the conserved active site tryptophan residue (Trp28) has a large effect on the protein stability, on the pKa of the nucleophilic cysteine and on the redox potential. Since these effects can either be due to the partiall...

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Identifiers

PMID: 19902501
DOI: 10.1002/pro.269
PMCID: PMC2817855

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19902501-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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