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Article

P-body components are required for Ty1 retrotransposition during assembly of retrotransposition-competent virus-like particles.

Molecular and cellular biology - 1 Jan 2010

Checkley Mary Ann, Nagashima Kunio, Lockett Stephen J, Nyswaner Katherine M, Garfinkel David J

Abstract excerpt

Ty1 is a retrovirus-like retrotransposon whose replication is influenced by diverse cellular processes in Saccharomyces cerevisiae. We have identified cytoplasmic P-body components encoded by DHH1, KEM1, LSM1, and PAT1 as cofactors that posttranscriptionally enhance Ty1 retrotransposition. Using fluorescent in situ hybridization and immunofluorescence microscopy, we found that Ty1 mRNA and Gag colocalize to...

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Source

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Identifiers

PMID: 19901074
DOI: 10.1128/MCB.00251-09
PMCID: PMC2798465

Genes

LSM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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