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Article

GNAS-associated disorders of cutaneous ossification: two different clinical presentations.

Bone - 1 Mar 2010

Schimmel R J, Pasmans S G M A, Xu M, Stadhouders-Keet S A E, Shore E M, Kaplan F S, Wulffraat N M

Abstract excerpt

Progressive osseous heteroplasia (POH) is a rare genetic disorder characterized by dermal ossification during infancy and progressive ossification into deep connective tissue during childhood. POH is at the severe end of a spectrum of GNAS-associated ossification disorders that include osteoma cutis and Albright Hereditary Osteodystrophy (AHO). Here we describe two girls who have different clinical presentations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19900597
DOI: 10.1016/j.bone.2009.11.001
PMCID: PMC3501213

Genes

GNAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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