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Article

Hematopoietic Cell Transplantation for Autoimmune Disease: Updates from Europe and the United States

5 Nov 2009

Abstract excerpt

Considerable advances have been made in our understanding of the immunobiology of autoimmune disease and its treatment with hematopoietic cell transplantation (HCT). In autoimmune disorders, the reconstituted immune system following lymphoablation and autologous HCT yields qualitative changes in immune defects and modifications in adaptive immune responses. Seminal experiments in animals demonstrated that...

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PMID: 19895895
DOI: 10.1016/j.bbmt.2009.10.034

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