Article
Divergent antimicrobial peptide (AMP) and acute phase protein (APP) responses to Trypanosoma congolense infection in trypanotolerant and trypanosusceptible cattle.
Molecular immunology - 1 Dec 2009
Meade Kieran G, O'Gorman Grace M, Hill Emmeline W, Narciandi Fernando, Agaba Morris, Kemp Stephen J, O'Farrelly Cliona, MacHugh David E
Abstract excerpt
African animal trypanosomiasis (AAT) is endemic across Sub-Saharan African and is a major constraint to livestock production. The ability of certain cattle breeds to remain productive despite infection is known as trypanotolerance; however, the underlying immune mechanisms contributing to this trait remain poorly understood. Antimicrobial peptides (AMPs) and acute phase proteins (APPs) are evolutionarily...
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