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Article

Five novel loci for inherited hearing loss mapped by SNP-based homozygosity profiles in Palestinian families.

European journal of human genetics : EJHG - 1 Apr 2010

Shahin Hashem, Walsh Tom, Rayyan Amal Abu, Lee Ming K, Higgins Jake, Dickel Diane, Lewis Kristen, Thompson James, Baker Carl, Nord Alex S, Stray Sunday, Gurwitz David, Avraham Karen B, King Mary-Claire, Kanaan Moien

Abstract excerpt

In communities with high rates of consanguinity and consequently high prevalence of recessive phenotypes, homozygosity mapping with SNP arrays is an effective approach for gene discovery. In 20 Palestinian kindreds with prelingual nonsyndromic hearing loss, we generated homozygosity profiles reflecting linkage to the phenotype. Family sizes ranged from small nuclear families with two affected children, one...

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Source

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Identifiers

PMID: 19888295
DOI: 10.1038/ejhg.2009.190
PMCID: PMC2987250

Genes

OTOA
CDH23
OTOF
PJVK
TECTA
TMPRSS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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