Article
Association of a common variant in TCF7L2 gene with type 2 diabetes mellitus in the Palestinian population.
Acta diabetologica - 1 Dec 2010
Ereqat Suheir, Nasereddin Abedelmajeed, Cauchi Stéphane, Azmi Kifaya, Abdeen Ziad, Amin Riyad
Abstract excerpt
Recent genome-wide association studies have provided an important resource for furthering our understanding of type 2 diabetes mellitus (T2DM) disease mechanisms. Most of these T2DM gene loci affect insulin secretion. We examined the association of rs7903146 variant in the transcription factor 7 like 2 gene (TCF7L2) with T2DM in 333 Palestinian subjects (219 were type 2 diabetic patients and 114 normoglycemic...
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