Article
inGAP: an integrated next-generation genome analysis pipeline.
Bioinformatics (Oxford, England) - 1 Jan 2010
Qi Ji, Zhao Fangqing, Buboltz Anne, Schuster Stephan C
Abstract excerpt
SUMMARY: We develop a novel mining pipeline, Integrative Next-generation Genome Analysis Pipeline (inGAP), guided by a Bayesian principle to detect single nucleotide polymorphisms (SNPs), insertion/deletions (indels) by comparing high-throughput pyrosequencing reads with a reference genome of related organisms. inGAP can be applied to the mapping of both Roche/454 and Illumina reads with no restriction of read...
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