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Article

Human von Willebrand factor gene and pseudogene: structural analysis and differentiation by polymerase chain reaction.

Biochemistry - 8 Jan 1991

Mancuso D J, Tuley E A, Westfield L A, Lester-Mancuso T L, Le Beau M M, Sorace J M, Sadler J E

Abstract excerpt

Structural analysis of the von Willebrand factor gene located on chromosome 12 is complicated by the presence of a partial unprocessed pseudogene on chromosome 22q11-13. The structures of the von Willebrand factor pseudogene and corresponding segment of the gene were determined, and methods were developed for the rapid differentiation of von Willebrand factor gene and pseudogene sequences. The pseudogene is 21-29...

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PMID: 1988024
DOI: 10.1021/bi00215a036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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