No association between transmembrane protein-tyrosine-phosphatase receptor type C (CD45) exon A 77C>G transversion and Hashimoto's thyroiditis in a German population.

doi:10.1016/j.humimm.2009.10.010

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

No association between transmembrane protein-tyrosine-phosphatase receptor type C (CD45) exon A 77C>G transversion and Hashimoto's thyroiditis in a German population.

Human immunology - 1 Feb 2010

Thude H, Weissenborn S, Vilser C, Müller U A, Kloos C, Wolf G, Beck J, Barz D

Abstract excerpt

The CD45 77C>G transversion (rs17612648) in exon A of the CD45 gene has been reported to be associated with the development of various autoimmune diseases. Because Hashimoto's thyroiditis (HT) is a typical autoimmune disease, we performed a study to determine the association of the 77C>G transversion with susceptibility to HT. We enrolled 170 patients and 230 healthy individuals in the study. The 77C>G...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Exons

Share to Gene Frequency

Share to Germany

Share to Hashimoto Disease

Share to Leukocyte Common Antigens

Share to Polymerase Chain Reaction

Share to Young Adult

Source

Open in PubMed

Identifiers

PMID: 19879912
DOI: 10.1016/j.humimm.2009.10.010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

No association between transmembrane protein-tyrosine-phosphatase receptor type C (CD45) exon A 77C>G transversion and Hashimoto's thyroiditis in a German population.PMID 19879912Read ↗

Disease associations and altered immune function in CD45 138G variant carriers.Semantic proximity Read ↗

No association of the CD45 77C>G transversion with inflammatory bowel disease in German patients.Semantic proximity Read ↗

A transmembrane protein-tyrosine phosphatase receptor type C (CD45) exon A point mutation (77 C to G) is not associated with the development of type 1 diabetes mellitus in a German population.Semantic proximity Read ↗

Updated analysis of studies on the cytotoxic T-lymphocyte-associated antigen-4 gene A49G polymorphism and Hashimoto's thyroiditis risk.Semantic proximity Read ↗

Cytotoxic T-lymphocyte associated antigen 4 polymorphism and Hashimoto's thyroiditis susceptibility: a meta-analysis.Semantic proximity Read ↗

Functional significance of the 77C --> G polymorphism in the human CD45 gene: enhanced T-cell reactivity by variantly expressed CD45RA isoforms.Semantic proximity Read ↗

Unusual case presentations associated with the CD45 C77G polymorphism.Semantic proximity Read ↗

Geographical distribution and disease associations of the CD45 exon 6 138G variant.Semantic proximity Read ↗

C77G in PTPRC (CD45) is no risk allele for ovarian cancer, but associated with less aggressive disease.Semantic proximity Read ↗

Does 77C-->G in PTPRC modify autoimmune disorders linked to the major histocompatibility locus?Semantic proximity Read ↗

The CTLA4 +49A/G polymorphism is associated with an increased risk of Hashimoto's thyroiditis in Asian but not Caucasian populations: an updated meta-analysis.Semantic proximity Read ↗

The −590CC Genotype in the IL4 Gene as a Strong Predictive Factor for the Development of Hypothyroidism in Hashimoto DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.