Premolar hypodontia is a common feature in Sotos syndrome with a mutation in the NSD1 gene.

Abstract excerpt

The major diagnostic manifestations in Sotos syndrome include frontal bossing, downward slanting palpebral fissures, a prominent jaw, learning disability, and childhood overgrowth. Over 90% of clinically diagnosed patients have an abnormality in the NSD1 gene. We investigated the dental manifestations of this disorder and found one or several premolar teeth were absent in 9 out of 13 (69%) affected children and...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Anodontia
• Share to Body Height
• Share to Body Weight