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Article

MK886-induced apoptosis depends on the 5-LO expression level in human malignant glioma cells.

Journal of neuro-oncology - 1 May 2010

Lim Jung Yeon, Oh Ji Hyeon, Jung Ju Ri, Kim Seong Muk, Ryu Chung Hun, Kim Hong-Tae, Jeun Sin-Soo

Abstract excerpt

Mounting evidence suggests that lipoxygenase (LO)-catalyzed products may play a key role in the development and progression of human cancers. In this study, we analyzed the effects of a 5-LO inhibitor, which inhibits the conversion of arachidonic acid to leukotrienes, on cell proliferation and ap...

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Share to Apoptosis Regulatory Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19862483
DOI: 10.1007/s11060-009-0036-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19862483-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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