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Article

A novel presenilin 1 mutation (Ser169del) in a Chinese family with early-onset Alzheimer's disease.

Neuroscience letters - 1 Jan 2010

Guo Jifeng, Wei Jiaohua, Liao Shusheng, Wang Lei, Jiang Hong, Tang Beisha

Abstract excerpt

Early-onset familial Alzheimer's disease (EOFAD) has been associated with mutations in three genes, of which presenilin 1 (PSEN1) mutations are the most frequent. Here we report a novel PSEN1 mutation in a Chinese family with autosomal dominant Alzheimer's disease with an onset age in the early 4...

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Source

Identifiers

PMID: 19853643
DOI: 10.1016/j.neulet.2009.10.055

Genes

PSEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19853643-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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