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Article

Functional metagenomics for enzyme discovery: challenges to efficient screening.

Current opinion in biotechnology - 1 Dec 2009

Uchiyama Taku, Miyazaki Kentaro

Abstract excerpt

Metagenomics has emerged as an alternative approach to conventional microbial screening that allows exhaustive screening of microbial genomes in their natural environments. Despite the potential usefulness of this approach, functional analysis of the metagenome is often problematic because of insufficient and biased expression of the cloned genes in Escherichia coli. This review highlights recent studies on the...

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PMID: 19850467
DOI: 10.1016/j.copbio.2009.09.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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