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Article

ATP-dependent stabilization and protection of fibroblast growth factor 2.

Journal of biotechnology - 1 Jan 2010

Rose Karsten, Gast Ronald E, Seeger Anna, Krieglstein Josef, Klumpp Susanne

Abstract excerpt

Fibroblast growth factor 2 (FGF2) plays a pivotal role in cell proliferation, angiogenesis and neuroprotection. Several clinical trials using this growth factor in bone regeneration, wound healing and cardioprotection are initiated but the inadequate stability of FGF2 after application is one major problem. Binding of ATP to FGF2 and other growth factors has been demonstrated recently. Here we report that ATP,...

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Source

Identifiers

PMID: 19836424
DOI: 10.1016/j.jbiotec.2009.10.005

Genes

FGF2

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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