Article
Gene profiling of clinical routine biopsies and prediction of survival in non-small cell lung cancer.
American journal of respiratory and critical care medicine - 15 Jan 2010
Baty Florent, Facompré Michaël, Kaiser Sergio, Schumacher Martin, Pless Miklos, Bubendorf Lukas, Savic Spasenija, Marrer Estelle, Budach Wolfgang, Buess Martin, Kehren Jeanne, Tamm Michael, Brutsche Martin H
Abstract excerpt
RATIONALE: Global gene expression analysis provides a comprehensive molecular characterization of non-small cell lung cancer (NSCLC). OBJECTIVES: To evaluate the feasibility of integrating expression profiling into routine clinical work-up by including both surgical and minute bronchoscopic biopsies and to develop a robust prognostic gene expression signature. METHODS: Tissue samples from 41 chemotherapy-naive...
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