Article
Meta-analysis of association between insertion/deletion polymorphism of the Angiotensin I-converting enzyme gene and venous thromboembolism.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis - 1 Feb 2011
Hsiao Fu-Chih, Hsu Lung-An
Abstract excerpt
An insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene accounts for 50% of the interindividual serum ACE level variation. Because the renin-angiotensin system regulates coagulation and vasoconstriction, it could have a role in venous thromboembolism (VTE). Several studies have evaluated the relationship between ACE I/D polymorphism and VTE, although the findings have been...
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