Article
Interaction between organochlorines and the AHR gene, and risk of non-Hodgkin lymphoma.
Cancer causes & control : CCC - 1 Jan 2010
Ng Carmen H, Janoo-Gilani Rozmin, Sipahimalani Payal, Gallagher Richard P, Gascoyne Randy D, Connors Joseph M, Weber Jean-Philippe, Lai Agnes S, Leach Stephen, Le Nhu D, Brooks-Wilson Angela R, Spinelli John J
Abstract excerpt
BACKGROUND: Plasma organochlorines have been implicated to increase the risk of non-Hodgkin lymphoma (NHL), and interaction with the aryl hydrocarbon receptor gene (AHR) may modify this risk. METHODS: In this case-control study conducted in British Columbia, Canada, five single nucleotide polymorphisms (SNPs) of AHR were genotyped in 422 NHL cases and 459 controls to measure the association between individual...
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