Article
Overview of genetics and obsessive-compulsive disorder.
Psychiatry research - 30 Nov 2009
Nicolini Humberto, Arnold Paul, Nestadt Gerald, Lanzagorta Nuria, Kennedy James L
Abstract excerpt
This paper reviews the current state of research into the genetics of obsessive-compulsive disorder (OCD). Heredity has a major role in OCD etiology. This evidence comes from several methodological approaches such as family, twin, and segregation analysis studies. A major single gene effect as well as a polygenic hypothesis has been suggested based on segregation studies. In addition, candidate gene association...
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