Primary Reconstruction of Alveolar Clefts Using Recombinant Human Bone Morphogenic Protein-2

Abstract excerpt

BACKGROUND: This novel method for primary alveolar cleft bony reconstruction avoids donor site morbidity and does not require close approximation of alveolar segments as necessitated by gingivoperiosteoplasty. The study aims to provide radiographic evidence of de novo synthesis of bone using recombinant human bone morphogenic protein-2 (rhBMP-2). METHODS: This institutional review board-approved class IV study...

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