Article
Association of functional gene polymorphism IL-1beta in patients with external apical root resorption.
American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics - 1 Oct 2009
Bastos Lages Elizabeth Maria, Drummond Alexandre Fortes, Pretti Henrique, Costa Fernando Oliveira, Lages Eugênio José Pereira, Gontijo Amanda Ianotta, Miranda Cota Luís Otávio, Brito Rui Barbosa
Abstract excerpt
INTRODUCTION: External apical root resorption (EARR) is a frequent complication of orthodontic treatment. Interleukin 1beta (IL-1beta) is a potent stimulus for bone resorption and osteoclastic cell recruitment during orthodontic tooth movement. The purpose of this study was to assess the association between a polymorphism in the IL-1beta genes and EARR during orthodontic treatment. METHODS: The sample included 61...
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