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Article

Current Perspectives on Role of Chromatin Modifications and Deacetylases in Lung Inflammation in COPD

1 Jan 2009

Abstract excerpt

Chromatin modifications and epigenetic regulation are critical for sustained and abnormal inflammatory response seen in lungs of patients with chronic obstructive pulmonary disease (COPD) because the activities of enzymes that regulate these epigenetic modifications are altered in response to cigarette smoke. Cigarette smoke induces chromatin modifications and epigenetic changes by causing post-translational...

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PMID: 19811389
DOI: 10.1080/15412550903049132

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