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Article

MicroRNA expression profiling of megakaryocytes in primary myelofibrosis and essential thrombocythemia

1 Jan 2009

Abstract excerpt

In primary myelofibrosis (PMF) and essential thrombocythemia (ET) the megakaryocytic lineage characteristically shows aberrant proliferation and maturation in which the regulatory microRNA (miR) system might be involved. Laser-microdissected PMF and ET megakaryocytes were analysed with real-time polymerase chain reaction (PCR) low density arrays comprising 365 microRNAs. The highest megakaryocytic expression...

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PMID: 19811223
DOI: 10.1080/09537100903114537

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