Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genotype at the P450scc locus determines differences in the amount of P450scc protein and maximal testosterone production in mouse Leydig cells.

Molecular endocrinology (Baltimore, Md.) - 1 Oct 1990

Nolan C J, Payne A H

Abstract excerpt

A genetic difference in maximal testosterone production in Leydig cells relates to differences in the genotype at the P450scc locus. The genetic relationship between the P450scc gene, the amount of Leydig cell P450scc protein, and maximal testosterone production was determined in the F2 generation of mice derived from SWR/J mice (SWR), a high Leydig cell testosterone-producing strain, and from C3H/HeJ (C3H), a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Chromosome Mapping
Share to Cyclic AMP

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genotype

Share to Homozygote

Share to Mice, Inbred C3H

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 1980936
DOI: 10.1210/mend-4-10-1459

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Genotype at the P450scc locus determines differences in the amount of P450scc protein and maximal testosterone production in mouse Leydig cells.PMID 1980936Read ↗

[Genetic control of the activity of microsomal enzymes of steroidogenesis in Leydig cells of inbred strains of mice].Semantic proximity Read ↗

Evidence of a steroidogenic enzyme gene dose effect on adrenal gene expression in hereditary rabbit congenital adrenal hyperplasia.Semantic proximity Read ↗

A single amino acid mutation (Ser180----Cys) determines the polymorphism in cytochrome P450g (P4502C13) by altering protein stability.Semantic proximity Read ↗

Deficient testicular and adrenal steroidogenesis in mutant cream (e/e) Syrian hamsters.Semantic proximity Read ↗

Inherited congenital adrenal hyperplasia in the rabbit is caused by a deletion in the gene encoding cytochrome P450 cholesterol side-chain cleavage enzyme.Semantic proximity Read ↗

Cloning and expression of complementary DNAs for multiple members of the human cytochrome P450IIC subfamilySemantic proximity Read ↗

Genetic susceptibility for C19 androgen induction of ovarian granulosa cell tumorigenesis in SWXJ strains of mice.Semantic proximity Read ↗

The genetics, pathophysiology, and management of human deficiencies of P450c17.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.