Article
Two alleles of NF-kappaB in the sea anemone Nematostella vectensis are widely dispersed in nature and encode proteins with distinct activities.
PloS one - 6 Oct 2009
Sullivan James C, Wolenski Francis S, Reitzel Adam M, French Courtney E, Traylor-Knowles Nikki, Gilmore Thomas D, Finnerty John R
Abstract excerpt
BACKGROUND: NF-kappaB is an evolutionarily conserved transcription factor that controls the expression of genes involved in many key organismal processes, including innate immunity, development, and stress responses. NF-kappaB proteins contain a highly conserved DNA-binding/dimerization domain called the Rel homology domain. METHODS/PRINCIPAL FINDINGS: We characterized two NF-kappaB alleles in the sea anemone...
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