X-linked myopia: Bornholm eye disease. Linkage to DNA markers on the distal part of Xq.

Article

X-linked myopia: Bornholm eye disease. Linkage to DNA markers on the distal part of Xq.

Clinical genetics - 1 Oct 1990

Schwartz M, Haim M, Skarsholm D

Abstract excerpt

Linkage analysis in a family with X-linked myopia gave a positive LOD score (z = 4.8 at theta = 0) for linkage to F8C. These results suggest a provisional assignment for the locus of this syndrome to the distal part of the X chromosome at Xq28. Based on the clinical and genetic evidence, a redefi...

Topics

Female
Genes, Recessive
Genetic Linkage
Genetic Markers
Humans
Male
Myopia
Pedigree
Phenotype
Polymorphism, Restriction Fragment Length
Sex Chromosome Aberrations
Syndrome
X Chromosome

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