Article
An assessment of a TNF polymorphic marker for the risk of HCV infection: meta-analysis and a new clinical study design.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Dec 2009
Chen Yun, Pei Jianping
Abstract excerpt
A number of studies have investigated the association between TNF-alpha -308G/A polymorphism and the risk of HCV infection; the results of these studies are conflict, however. To provide a more definitive conclusion, a meta-analysis combining and summarizing 12 studies was performed. The Mantel-Haenszel and DerSimonian-Laird methods were employed in traditional fixed effects and random effects meta-analysis,...
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