Article
[Genetic polymorphisms of alcohol dehydrogenase-2 and aldehyde dehydrogenase-2 associated with the susceptibility on esophageal cancer].
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi - 1 May 2009
Ding Jian-hua, Li Su-ping, Cao Hai-xia, Wu Jian-zhong, Gao Chang-ming, Su Ping, Liu Yan-ting, Zhou Jian-nong, Chang Jun, Yao Gen-hong
Abstract excerpt
OBJECTIVE: To evaluate the impact of alcohol dehydrogenase-2 (ADH2) and aldehyde dehydrogenase-2 (ALDH2) polymorphisms on the susceptibility of esophageal cancer. METHODS: A case-control study including 221 cases of esophageal cancer and 191 controls was carried out in Taixing city of Jiangsu province. ADH2 and ALDH2 genotypes were tested by PCR and denaturing high performance liquid chromatography (DHPLC)....
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