Article
[Entecavir resistance in entecavir naive lamivudine treated chronic hepatitis B patients].
Mikrobiyoloji bulteni - 1 Jul 2009
Sayan Murat, Hülagü Sadettin, Akhan Sila Cetin, Sentürk Omer, Meriç Meliha, Cekmen Mustafa
Abstract excerpt
Approved hepatitis B virus (HBV) therapies include interferon-alpha and nucleos(t)ide analogues. Lamivudine (LVD) is a nucleoside analogue and following long term LVD therapy, resistance emerges in a significant number of patients. Entecavir (ETV) is a novel deoxyguanosine analogue with potent activity against HBV in chronically infected patients. ETV is highly efficacious in treating nucleoside naive and LVD...
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