Article
Characterization of resistance to the protease inhibitor boceprevir in hepatitis C virus-infected patients.
Hepatology (Baltimore, Md.) - 1 Dec 2009
Susser Simone, Welsch Christoph, Wang Yalan, Zettler Markus, Domingues Francisco S, Karey Ursula, Hughes Eric, Ralston Robert, Tong Xiao, Herrmann Eva, Zeuzem Stefan, Sarrazin Christoph
Abstract excerpt
UNLABELLED: Boceprevir is a hepatitis C virus (HCV) nonstructural protein (NS) 3/4A protease inhibitor that is currently being evaluated in combination with peginterferon alfa-2b and ribavirin in phase 3 studies. The clinical resistance profile of boceprevir is not characterized in detail so far....
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