Article
AI-2 quorum-sensing inhibitors affect the starvation response and reduce virulence in several Vibrio species, most likely by interfering with LuxPQ.
Microbiology (Reading, England) - 1 Dec 2009
Brackman Gilles, Celen Shari, Baruah Kartik, Bossier Peter, Van Calenbergh Serge, Nelis Hans J, Coenye Tom
Abstract excerpt
The increase of disease outbreaks caused by Vibrio species in aquatic organisms as well as in humans, together with the emergence of antibiotic resistance in Vibrio species, has led to a growing interest in alternative disease control measures. Quorum sensing (QS) is a mechanism for regulating microbial gene expression in a cell density-dependent way. While there is good evidence for the involvement of...
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