Article
Matrix metalloproteinase-3 gene polymorphism in renal transplant patients with gingival overgrowth.
Journal of periodontal research - 1 Feb 2010
Drozdzik A, Kurzawski M, Lener A, Kozak M, Banach J, Drozdzik M
Abstract excerpt
BACKGROUND AND OBJECTIVE: Gingival enlargement frequently occurs in transplant patients receiving immunosuppressive drugs. It was hypothesized that gingival enlargement associated with cyclosporine use results from reduced degradation of extracellular matrix in the gingiva. Matrix metalloproteinase-3 (MMP-3) is involved in biodegradation of the extracellular matrix, and its inhibition may contribute to an...
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