Article
Associations between restriction fragment length polymorphisms detected with a probe for human C4 and allotype of C4B5 allele.
Human immunology - 1 Sept 1990
Kobayashi K, Atoh M, Hara M, Tanaka H, Itoh K, Hirakawa K, Sekiguchi S
Abstract excerpt
We studied the fourth component of human complement (C4) allotypes in 58 Japanese individuals. The technique of Southern, with C4 and 21-OH cDNA probes, was used to examine the genomic DNA of 45 individuals typed for C4 by protein electrophoresis. Novel HindIII C4 10- and 5-kb and EcoRI C4 13-Kb restriction fragments were identified in each of nine Japanese individuals. The novel fragments were different from the...
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