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Non- spa -Typeable Clinical Staphylococcus aureus Strains Are Naturally Occurring Protein A Mutants

17 Sept 2009

Abstract excerpt

Staphylococcus aureus is a major human pathogen responsible for increasing the prevalence of community- and hospital-acquired infections. Protein A (SpA) is a key virulence factor of S. aureus and is highly conserved. Sequencing of the variable-number tandem-repeat region of SpA (spa typing) provides a rapid and reliable method for epidemiological studies. Rarely, non-spa-typeable S. aureus strains are...

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PMID: 19759222
DOI: 10.1128/jcm.00941-09

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