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Article

Epiblast-derived stem cells in embryonic and adult tissues

1 Jan 2009

Abstract excerpt

Pluripotent cells can be isolated from the mammalian inner cell mass (ICM) of the embryo at the blastocyst stage, and maintained in culture as undifferentiated, embryonic stem cells (ES). These cells are an important model of mammalian development in vitro and are the focus of a great deal of research for their use in Cell Therapy. In vivo, shortly after the blastocyst stage, the ICM segregates into two layers:...

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PMID: 19757397
DOI: 10.1387/ijdb.072413md

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