Article
Identification of transcription start sites and preferential expression of select CB2 transcripts in mouse and human B lymphocytes.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology - 1 Dec 2009
Sherwood Tracy A, Nong Liang, Agudelo Marisela, Newton Cathy, Widen Ray, Klein Thomas W
Abstract excerpt
Marijuana cannabinoids, the endocannabinoids, and cannabinoid cell receptors have been shown to play important roles in immune regulation particularly as potent modulators of anti-inflammatory cytokines. The predominant cannabinoid receptor involved in this immune regulation is cannabinoid receptor 2 (CB(2)), which is predominantly expressed in B lymphocytes. However, the promoter region and mechanisms of CB(2)...
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