Article
Basement membranes and human disease.
Cell and tissue research - 1 Jan 2010
Van Agtmael Tom, Bruckner-Tuderman Leena
Abstract excerpt
In 1990, the role of basement membranes in human disease was established by the identification of COL4A5 mutations in Alport's syndrome. Since then, the number of diseases caused by mutations in basement membrane components has steadily increased as has our understanding of the roles of basement membranes in organ development and function. However, many questions remain as to the molecular and cellular...
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