Article
Use of massive parallel pyrosequencing for near full-length characterization of a unique HIV Type 1 BF recombinant associated with a fatal primary infection.
AIDS research and human retroviruses - 1 Sept 2009
Bruselles Alessandro, Rozera Gabriella, Bartolini Barbara, Prosperi Mattia, Del Nonno Franca, Narciso Pasquale, Capobianchi Maria R, Abbate Isabella
Abstract excerpt
Near full length genome characterization of a BF recombinant from a patient who died from multiorgan failure during HIV-1 seroconversion is reported. Massive parallel pyrosequencing was used with the shotgun approach. Intrahost genetic variability along the whole genome was calculated and coreceptor usage of viral quasispecies was predicted. A consensus sequence was established to perform subtype assignment,...
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