Article
Association studies of erythroid alpha-spectrin at the tetramerization site.
British journal of haematology - 1 Nov 2009
Lam Vinh Q, Antoniou Chloe, Rolius Ramunas, Fung Leslie W-M
Abstract excerpt
The functional roles of residues 21-43 and 55-59 in the alpha-spectrin N-terminal region in forming tetramers were determined by the introduction of mutations at each of these positions. We measured association affinities for tetramer formation (K(d)), which can be used to predict clinical severi...
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