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Article

Studies of the L-myc DNA polymorphism and relation to metastasis in Norwegian lung cancer patients.

British journal of cancer - 1 Jun 1990

Tefre T, Børresen A L, Aamdal S, Brøgger A

Abstract excerpt

We studied 83 lung cancer patients and 129 controls for the EcoRI polymorphism of the L-myc gene. No association was found between the L-myc RFLP and increased risk of metastasis, either to lymph nodes or metastasis to other organs. There was no difference in survival time between the three different genotypes. The S-allele of the L-myc RFLP has been correlated to increased metastasis in lung cancer. We found no...

Topics

Adenocarcinoma
Adult
Aged
Aged, 80 and over
Alleles
Carcinoma, Non-Small-Cell Lung
Carcinoma, Small Cell
Carcinoma, Squamous Cell
Female
Genotype
Humans
Lung Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Neoplasm Metastasis

Oncogenes

Polymorphism, Restriction Fragment Length

Source

Open in PubMed Open full text

Identifiers

PMID: 1973618
DOI: 10.1038/bjc.1990.182
PMCID: PMC1971690

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1973618-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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