Article
Frequency of Val1016Ile mutation in the voltage-gated sodium channel gene of Aedes aegypti Brazilian populations.
Tropical medicine & international health : TM & IH - 1 Nov 2009
Martins Ademir Jesus, Lima José Bento Pereira, Peixoto Alexandre Afranio, Valle Denise
Abstract excerpt
One of the major insect pyrethroid resistance mechanisms affects its target site, the voltage-gated sodium channel (Na(v)). In Aedes aegypti, the Val1016Ile substitution of the AaNa(v) gene is associated to resistance in several Latin American countries. Genotyping of susceptible and resistant mosquitoes from seven Brazilian localities detected the 1016Ile mutation in five populations with a higher frequency of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
