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Article

Contribution of occlusal activity to synaptogenesis in masticatory muscles.

Journal of dental research - 1 Aug 2009

Kota Y, Yamane A, Tomohiro T, Asada Y

Abstract excerpt

Synaptogenesis in the neuromuscular junction involves a nicotinic acetylcholine receptor (nAChR) switch and elimination. The microphthalmic mouse (mi/mi) with a mutation in the mitf gene cannot perform occlusal activity, because its teeth do not erupt. The present study attempted to elucidate the contribution of occlusal activity to synaptogenesis in masticatory muscles. In the masseter of the mi/mi, the nAChR...

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PMID: 19734467
DOI: 10.1177/0022034509341738

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