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mRNA expression profiles show differential regulatory effects of microRNAs between estrogen receptor-positive and estrogen receptor-negative breast cancer

1 Sept 2009

Abstract excerpt

BACKGROUND: Recent studies have shown that the regulatory effect of microRNAs can be investigated by examining expression changes of their target genes. Given this, it is useful to define an overall metric of regulatory effect for a specific microRNA and see how this changes across different conditions. RESULTS: Here, we define a regulatory effect score (RE-score) to measure the inhibitory effect of a microRNA in...

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PMID: 19723326
DOI: 10.1186/gb-2009-10-9-r90

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