Article
DNA polymorphism of the C2 and factor B gene.
Experimental and clinical immunogenetics - 1 Jan 1990
Cross S J, Thomson W
Abstract excerpt
C2 and factor B are encoded by very closely linked loci in the class III region of the human major histocompatibility complex on chromosome 6. The factor B gene is divided into 18 exons, and is 6 kb in length whereas the C2 gene is much larger being 18 kb in length. Sequence and Southern blot ana...
Topics
- Alleles
- Blotting, Southern
- Chromosomes, Human, Pair 6
- Complement C2
- Complement Factor B
- Electrophoresis
- Enzyme Precursors
- HLA Antigens
- Haplotypes
- Humans
- Major Histocompatibility Complex
- Polymorphism, Restriction Fragment Length
- Restriction Mapping