Article
DNA polymorphism of the C2 and factor B gene.
Experimental and clinical immunogenetics - 1 Jan 1990
Cross S J, Thomson W
Abstract excerpt
C2 and factor B are encoded by very closely linked loci in the class III region of the human major histocompatibility complex on chromosome 6. The factor B gene is divided into 18 exons, and is 6 kb in length whereas the C2 gene is much larger being 18 kb in length. Sequence and Southern blot analysis has defined 5 DNA polymorphisms in the DNA encompassing the C2 and factor B loci. The most interesting of these...
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