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Heterogeneous Nuclear Ribonucleoprotein A1 Is Identified as a Potential Biomarker for Colorectal Cancer Based on Differential Proteomics Technology

28 Aug 2009

Abstract excerpt

Colorectal cancer (CRC) is the third most common cancer worldwide and has poor prognosis. To identify the proteins involved in colorectal carcinogenesis, we employed 2-DE and MALDI-TOF/TOF-based proteomics approach to study the differentially expressed proteins in tumor and adjacent nontumor tissue samples. Samples from 10 colorectal patients were analyzed. Of the 7 significantly and consistently altered proteins...

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PMID: 19715280
DOI: 10.1021/pr900365e

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