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Article

Fission yeast IQGAP arranges actin filaments into the cytokinetic contractile ring.

The EMBO journal - 21 Oct 2009

Takaine Masak, Numata Osamu, Nakano Kentaro

Abstract excerpt

The contractile ring (CR) consists of bundled actin filaments and myosin II; however, the actin-bundling factor remains elusive. We show that the fission yeast Schizosaccharomyces pombe IQGAP Rng2 is involved in the generation of CR F-actin and required for its arrangement into a ring. An N-terminal fragment of Rng2 is necessary for the function of Rng2 and is localized to CR F-actin. In vitro the fragment...

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Identifiers

PMID: 19713940
DOI: 10.1038/emboj.2009.252
PMCID: PMC2771088

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Fission yeast IQGAP arranges actin filaments into the cytokinetic contractile ring.PMID 19713940Read ↗

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