Article
Haplotype-based case-control study of receptor (calcitonin) activity-modifying protein-1 gene in cerebral infarction.
Journal of human hypertension - 1 May 2010
Nakazato T, Nakayama T, Naganuma T, Sato N, Fu Z, Wang Z, Soma M, Sugama K, Hinohara S, Doba N
Abstract excerpt
Calcitonin gene-related peptide (CGRP) receptor is a complex molecule that consists of calcitonin receptor-like receptor and receptor activity-modifying protein-1 (RAMP1). It was recently reported that RAMP1-deficient mice (RAMP1(-/-)) showed inflammatory responses with a transiently significant increase in serum CGRP levels and proinflammatory cytokines when compared with RAMP1(+/+) mice. The aim of this study...
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